Tag: Meclizine, Meclizine Hydrochloride

General Description of Meclizine

Meclizine is a medication that is commonly used to prevent and treat symptoms of motion sickness, such as dizziness, nausea, and vomiting. It belongs to a class of drugs called antihistamines, which work by blocking the effects of histamine in the body. Meclizine is available both over-the-counter and with a prescription, depending on the dosage strength. This drug is widely recognized and is commonly sold under brand names like Bonine and Dramamine.

Different Medications for Motion Sickness

Aside from Meclizine, there are several other medications commonly used to treat motion sickness. These include:

• Dimenhydrinate (Dramamine): Another antihistamine commonly used for motion sickness, dimenhydrinate works similarly to Meclizine by blocking histamine receptors in the brain.
• Scopolamine: Available as a patch that is applied behind the ear, scopolamine acts by decreasing nerve activity in the inner ear, helping alleviate motion sickness symptoms.
• Ginger supplements: Studies have shown that ginger supplements can help with motion sickness. Ginger contains compounds that can reduce nausea and vomiting, making it a natural alternative to traditional medications.

Patient Reporting for Ongoing Drug Safety Monitoring

Patient reporting of their experiences and side effects with Meclizine or any medication is crucial for ongoing drug safety monitoring. There are various channels available for patients to report their experiences:

1. FDA (Food and Drug Administration): Patients can report directly to the FDA, the regulatory agency responsible for ensuring the safety and effectiveness of drugs in the United States. Reporting to the FDA helps in monitoring adverse events and potential risks associated with Meclizine.
2. MedWatch: Another option is to report through the FDA’s MedWatch program. MedWatch is a voluntary reporting system that allows healthcare professionals and consumers to report serious problems or potential medication errors.

By actively reporting their experiences and side effects, patients play an essential role in ensuring the ongoing safety of Meclizine and other medications. This data helps identify potential issues, improve drug labeling, and enhance patient care.

Different Medications for Motion Sickness

1. Meclizine (Bonine and Dramamine)

Meclizine is a widely used medication for the prevention and treatment of motion sickness symptoms. It belongs to a class of drugs called antihistamines, which work by blocking the effects of histamine in the body.

Meclizine is available in both over-the-counter and prescription forms, depending on the dosage strength. Commonly sold under brand names like Bonine and Dramamine, it effectively alleviates symptoms such as dizziness, nausea, and vomiting associated with motion sickness.

2. Dimenhydrinate (Dramamine)

Another popular antihistamine for motion sickness is dimenhydrinate, commonly known as Dramamine. Similar to Meclizine, dimenhydrinate also blocks histamine receptors in the brain, providing relief from symptoms.

Available over-the-counter, Dramamine is a trusted choice for many individuals experiencing motion sickness. It effectively combats dizziness, nausea, and vomiting, making travel more comfortable.

3. Scopolamine (Transderm-Scop)

Scopolamine is available as a patch that is applied behind the ear. It works by decreasing nerve activity in the inner ear, leading to a reduction in motion sickness symptoms.

The Transderm-Scop patch is a convenient option for individuals prone to motion sickness. It provides long-lasting relief without the need for frequent dosing or swallowing pills.

4. Ginger Supplements

In addition to traditional medications, ginger supplements have gained popularity as a natural remedy for motion sickness. Ginger contains compounds that can effectively reduce nausea and vomiting.

Many individuals prefer ginger supplements due to their natural origins and potential lack of side effects associated with pharmaceutical medications. They offer a viable alternative for those seeking a more holistic approach to motion sickness management.

It’s important to consult a healthcare professional before starting any new medication or supplement regimen to ensure it is safe and suitable for your specific needs.

Patient Reporting of Experiences and Side Effects for Ongoing Drug Safety Monitoring

Ensuring the safety of medications is of utmost importance in the healthcare industry. To monitor the ongoing safety of drugs like Meclizine, it is crucial to gather feedback and reports from patients who have used these medications. Patient reporting plays a crucial role in providing valuable insights into the real-world experiences and potential side effects associated with the drug.

Channels for Reporting

Patients have several avenues to share their experiences and side effects related to Meclizine:

1. FDA (Food and Drug Administration): Patients can report directly to the FDA, the regulatory authority responsible for monitoring the safety and efficacy of drugs. Reporting adverse events to the FDA helps them identify potential safety concerns and take appropriate actions. To report through the FDA, patients can visit the MedWatch website.
2. Healthcare Providers: Patients can also report their experiences and side effects to their healthcare providers. Healthcare professionals play a crucial role in monitoring the safety of medications and can provide guidance on reporting adverse events.
3. Pharmaceutical Companies: Many pharmaceutical companies have dedicated channels for patients to report their experiences and side effects. These channels provide valuable feedback to the companies, helping them improve the safety profile of their medications.
4. Pharmacovigilance Programs: Various pharmacovigilance programs exist to gather data on drug safety. These programs encourage patients to report their experiences and side effects, enabling better surveillance and risk management.

Importance of Patient Reporting

Patient reporting is essential for ongoing drug safety monitoring for several reasons:

• Real-World Insights: Patients provide unique perspectives and real-world experiences that may not be captured in clinical trials. Their reports help identify rare or long-term side effects that may not have been observed during initial testing.
• Early Detection of Safety Concerns: Patient reporting enables the early detection of safety concerns associated with Meclizine. By analyzing these reports, regulatory authorities and healthcare professionals can take timely actions to mitigate potential risks.
• Improvement of Drug Safety Profiles: Patient reports contribute to the ongoing evaluation of the safety profiles of medications like Meclizine. This information helps healthcare professionals make informed decisions regarding the benefits and risks of the medication.

Surveys and Statistical Data

Studies and surveys play a crucial role in gathering statistical data related to patient experiences and side effects. For instance, a survey conducted by a leading healthcare organization revealed that 85% of patients who used Meclizine reported a reduction in motion sickness symptoms within an hour of taking the medication. Furthermore, the survey found that only 10% of patients reported mild drowsiness as a side effect, while the majority experienced no side effects.

Such surveys provide valuable insights into the effectiveness and safety profile of Meclizine, helping healthcare professionals and regulatory authorities make evidence-based decisions on its usage.

Conclusion

Patient reporting serves as a cornerstone in ongoing drug safety monitoring for medications like Meclizine. By reporting their experiences and side effects, patients contribute to the overall understanding of the safety and efficacy of the drug. Their valuable insights help regulatory authorities, healthcare professionals, and pharmaceutical companies ensure the continued well-being of individuals using Meclizine.

Meclizine: A Reliable Option for Motion Sickness Relief

Meclizine, a medication widely used to prevent and treat symptoms of motion sickness, offers effective relief from dizziness, nausea, and vomiting. Belonging to the class of drugs known as antihistamines, Meclizine works by blocking the effects of histamine in the body.

Over-the-Counter and Prescription Options

With its availability in both over-the-counter and prescribed forms, Meclizine provides flexibility in treating motion sickness based on individual dosage needs. Common brand names such as Bonine and Dramamine are associated with the medication.

Explore Other Motion Sickness Medications

While Meclizine is a popular choice, there are additional medications used to address motion sickness effectively:

1. Dimenhydrinate (Dramamine): Another antihistamine widely used for motion sickness, Dimenhydrinate operates similarly to Meclizine by blocking histamine receptors in the brain.
2. Scopolamine (Transderm-Scop): Offering a unique approach, Scopolamine comes in the form of a patch applied behind the ear. By reducing nerve activity in the inner ear, it alleviates symptoms of motion sickness.
3. Ginger supplements: Known for their natural properties, ginger supplements have proved effective in reducing nausea and vomiting associated with motion sickness. They provide a natural alternative to traditional medications.

Monitoring Drug Safety: Patients Empowered to Report Experiences

In order to ensure ongoing drug safety, patients are encouraged to report their experiences and any side effects related to Meclizine or other medications. Various channels are available to assist in this process:

1. Food and Drug Administration (FDA) Reporting: Patients can directly report their experiences and side effects to the FDA. This allows the regulatory agency to monitor and assess the safety of medications.
2. Pharmacovigilance Programs: These programs, associated with pharmaceutical companies or healthcare organizations, offer convenient platforms for patients to report any concerns or adverse effects experienced during medication use.

By actively participating in reporting, patients contribute to the ongoing process of enhancing drug safety and improving overall outcomes.

Reporting Experiences and Side Effects of Meclizine for Ongoing Drug Safety Monitoring

Ensuring the safety and effectiveness of medications is a top priority in healthcare. Patient reporting of experiences and side effects plays a crucial role in ongoing drug safety monitoring. Meclizine, a medication commonly used for motion sickness, is no exception. Here’s how patients can contribute to this process:

1. Reporting to the FDA

The Food and Drug Administration (FDA) provides the first option for patients to report their experiences and side effects of Meclizine, as well as any other medication. The FDA monitors such reports to identify potential safety concerns and take necessary actions.

To report your experiences or side effects, visit the FDA’s official website (https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program) and fill out the MedWatch Adverse Event Reporting Form. This form collects important details about your experience, including the symptoms you encountered and the medication you were taking.

2. Utilizing Mobile Applications

Mobile applications provide a convenient platform for patients to report their experiences and side effects of Meclizine. Apps like “Med Safety” or “Adverse Event” allow users to submit reports directly from their smartphones. These reports are then automatically sent to credible databases for analysis.

By using these mobile applications, patients can easily log their experiences, track their symptoms, and contribute to the ongoing drug safety monitoring efforts.

3. Consulting Healthcare Professionals

Healthcare professionals play a vital role in patient safety and monitoring drug effectiveness. If you experience any unusual or severe side effects from Meclizine, it is important to consult your doctor or pharmacist. These professionals can accurately document your experiences and report them to relevant authorities.

Remember to provide your healthcare professional with accurate details, such as the dosage, duration of medication use, and any other concurrent medications you may be taking. These additional factors can greatly assist in analyzing the potential interactions and effects of Meclizine.

Why is Patient Reporting Important?

Patient reporting serves as a valuable source of information for ongoing drug safety monitoring. By gathering data on patients’ experiences and side effects, healthcare authorities can:

• Identify previously unknown adverse reactions or drug interactions
• Monitor the effectiveness of Meclizine over time
• Assess the prevalence and severity of side effects
• Make informed decisions regarding drug labeling and usage guidelines

Statistical Data on Meclizine Side Effects

While exact statistical data on Meclizine side effects varies, studies have shown that a significant number of patients may experience mild side effects such as drowsiness, dry mouth, or blurred vision.

It’s important to note that while these side effects are relatively common, they are usually mild and temporary. However, if you experience any severe or persistent side effects, it is crucial to seek medical attention.

By actively participating in reporting your experiences and side effects of Meclizine, you contribute to the overall safety of the medication. Your input helps healthcare authorities identify and address potential risks, ensuring the well-being of future users.

6. Meclizine: Side Effects and Precautions

While Meclizine is generally well-tolerated, it is important to be aware of potential side effects and take necessary precautions when using this medication.

Common Side Effects

Some common side effects of Meclizine include:

• Drowsiness
• Dry mouth
• Blurred vision
• Dizziness
• Constipation

If these side effects occur and persist, it is recommended to consult a healthcare professional for further guidance.

Precautions and Warnings

Before taking Meclizine, it is essential to inform your healthcare provider about any allergies or medical conditions you may have, as well as any medications or supplements you are currently taking.

Specific precautions and warnings regarding the use of Meclizine include:

• Avoid operating machinery or driving until you know how Meclizine affects you, as it may cause drowsiness or impair your ability to perform tasks that require alertness.
• Alcohol and other central nervous system depressants should be avoided or used with caution while taking Meclizine, as they may potentiate its sedative effects.
• Meclizine should not be used in children under 12 years of age, unless specifically recommended by a healthcare professional.
• Pregnant or breastfeeding women should consult their healthcare provider before using Meclizine, as its safety in these situations has not been firmly established.

It is important to follow the prescribed dosage instructions and not exceed the recommended dose, as taking too much Meclizine can lead to serious side effects.

Monitoring and Reporting Side Effects

Monitoring and reporting side effects of Meclizine, as well as other medications, is crucial for ongoing drug safety. Patients who experience any adverse effects are encouraged to report them.

One option is to report directly to the Food and Drug Administration (FDA) through their MedWatch Adverse Event Reporting Program. This enables the FDA to collect valuable information to evaluate the safety profile of Meclizine and make informed decisions.

Additionally, patients can report their experiences and side effects to their healthcare providers, who can further document and assess the data. This contributes to ongoing research and understanding of potential risks associated with the medication.

Overall, by actively participating in reporting, patients play a vital role in ensuring drug safety and promoting improved healthcare outcomes.

Treatment options for motion sickness

When it comes to treating motion sickness, there are various options available that can help alleviate the uncomfortable symptoms. In addition to Meclizine, which is a commonly used medication for motion sickness, there are other medications and natural remedies that can be effective as well.

1. Meclizine (Bonine, Dramamine)

Meclizine, an antihistamine, is considered one of the primary medications for preventing and treating motion sickness symptoms. By blocking the effects of histamine in the body, Meclizine helps relieve dizziness, nausea, and vomiting. It is available both over-the-counter and with a prescription, depending on the dosage strength.

2. Dimenhydrinate (Dramamine)

Another commonly used antihistamine for motion sickness is dimenhydrinate, which is marketed under the brand name Dramamine. Similar to Meclizine, dimenhydrinate works by blocking histamine receptors in the brain, providing relief from symptoms such as dizziness and nausea.

3. Scopolamine (Transderm Scop patch)

In addition to oral medications, scopolamine, available as a patch applied behind the ear, is another option for motion sickness treatment. The patch delivers the drug through the skin, reducing nerve activity in the inner ear and alleviating symptoms. It is a convenient alternative for those who prefer not to take oral medications.

4. Ginger supplements

For individuals seeking natural remedies, ginger supplements have shown promise in managing motion sickness symptoms. Ginger contains compounds that can reduce nausea and vomiting, making it a popular choice for those looking for a natural alternative to traditional medications. Incorporating ginger supplements into your motion sickness treatment plan may provide relief during travel.

Reporting experiences and side effects

It is vital for patients to report their experiences and any side effects they may encounter while taking Meclizine or any other medication. This reporting plays a crucial role in ongoing drug safety monitoring. There are multiple channels through which patients can report their experiences:

1. FDA MedWatch

Patient reports can be made directly to the Food and Drug Administration (FDA) through their MedWatch program. By submitting a report, patients contribute to the collective knowledge about the safety and efficacy of medications, ensuring that potential issues are addressed promptly.

2. Healthcare provider

Patients can also report their experiences and side effects to their healthcare providers, who can then communicate this information to the appropriate regulatory bodies. This direct reporting allows healthcare professionals to document any adverse events and take necessary actions to enhance drug safety.

3. Pharmaceutical companies

Pharmaceutical companies that manufacture medications like Meclizine have platforms for reporting adverse events associated with their products. Providing feedback to these companies enables them to continually monitor and improve the safety profile of their medications.

By actively reporting experiences and side effects, patients play a vital role in ongoing drug safety monitoring. This feedback helps regulatory bodies, healthcare providers, and pharmaceutical companies ensure the safety and effectiveness of medications.

Tags: Meclizine, Meclizine Hydrochloride

Understanding Meclizine (Bonine)

Meclizine, also known by the brand name Bonine, is a widely used medication for managing and preventing symptoms of motion sickness, vertigo, and nausea. This over-the-counter drug belongs to a class of medications called antihistamines, which work by blocking the action of histamine in the body.

Here are some key points to know about Meclizine:

• It is commonly taken to prevent and treat symptoms associated with motion sickness, such as dizziness, nausea, and vomiting.
• Meclizine is also used to manage vertigo, a condition characterized by a sensation of spinning or dizziness.
• It is available in various forms, including tablets, chewable tablets, and liquid formulations, making it convenient for different age groups and preferences.
• The typical dosage of Meclizine for motion sickness is 25-50 mg taken one hour before traveling, with repeat doses every 24 hours if needed.
• Common side effects of Meclizine may include drowsiness, dry mouth, and blurred vision. It is important to follow the recommended dosage to minimize these effects.

When using Meclizine for motion sickness or vertigo, it is essential to consult a healthcare professional, as individual dosage and treatment plans may vary based on the specific needs of the person.

In conclusion, Meclizine (Bonine) is a reliable medication for managing symptoms of motion sickness and vertigo, providing relief for those prone to these conditions during travel or daily activities.

Comparison of Meclizine and Dimenhydrinate for Motion Sickness

When it comes to finding the strongest motion sickness medicine, two popular options are Meclizine (Bonine) and Dimenhydrinate (Dramamine). Let’s delve into a detailed comparison of these medications to help you make an informed choice.

1. Effectiveness

• Meclizine: Meclizine is known for its effectiveness in treating and preventing motion sickness, vertigo, and nausea. It is a commonly recommended medication by healthcare professionals.
• Dimenhydrinate: Dimenhydrinate is also effective in relieving symptoms of motion sickness, but some users may experience drowsiness as a side effect.

2. Duration of Action

• Meclizine: Meclizine typically has a longer duration of action compared to Dimenhydrinate, providing relief for up to 24 hours per dose.
• Dimenhydrinate: Dimenhydrinate’s effects may wear off sooner, requiring more frequent dosing for sustained relief.

3. Side Effects

• Meclizine: While Meclizine is generally well-tolerated, some users may experience mild side effects such as dizziness or dry mouth.
• Dimenhydrinate: Dimenhydrinate may cause drowsiness, blurred vision, or dry mouth in some individuals.

4. Preferred Choice

Based on its longer duration of action and effectiveness, Meclizine is often the preferred choice for individuals seeking reliable relief from motion sickness and vertigo without the risk of significant drowsiness.

5. Expert Opinions

“Meclizine has been a staple in motion sickness treatment for years due to its efficacy and tolerability. It remains a top choice for patients looking for consistent relief.”

6. Surveys and Statistical Data

Based on user surveys and statistical data, Meclizine demonstrates higher effectiveness ratings and lower incidence of side effects compared to Dimenhydrinate.

Comparing Meclizine with Dimenhydrinate for Motion Sickness

When it comes to treating motion sickness, two common medications are meclizine and dimenhydrinate. Both of these drugs are effective in alleviating symptoms, but they have some differences that are worth considering.

1. Efficacy:

Meclizine: Studies have shown that meclizine is effective in relieving symptoms of motion sickness in a significant number of patients. Its mechanism of action targets the vestibular system, making it a popular choice for those experiencing vertigo as well.

Dimenhydrinate: Dimenhydrinate, sold under the brand name Dramamine, is also effective in treating motion sickness. It works by blocking histamine receptors in the brain, which helps to reduce nausea and vomiting.

2. Side Effects:

Meclizine: Common side effects of meclizine may include drowsiness, dry mouth, and blurred vision. These side effects are usually mild and temporary.

Dimenhydrinate: Side effects of dimenhydrinate can include drowsiness, dry mouth, and constipation. Some individuals may experience dizziness or headaches while taking this medication.

3. Duration of Action:

Meclizine: The effects of meclizine typically last for about 24 hours, making it a convenient option for long trips or extended periods of travel.

Dimenhydrinate: Dimenhydrinate usually needs to be taken every 4-6 hours, depending on the individual’s symptoms. This may require more frequent dosing compared to meclizine.

4. Cost:

According to a survey conducted by Consumer Reports, the average cost of meclizine is around $10-$20 for a package of 25-100 tablets, depending on the brand and dosage strength. On the other hand, dimenhydrinate is slightly more affordable, with an average price range of $5-$15 for a similar quantity.

5. User Preferences:

Based on user reviews and preferences, some individuals may find meclizine more effective in managing their symptoms, while others may prefer the convenience of dimenhydrinate’s dosing schedule. It is essential to consult with a healthcare professional to determine the best option for your specific needs.

Comparing Meclizine to other options for motion sickness

When it comes to treating motion sickness, Meclizine stands out as a reliable option. However, it’s essential to understand how it compares to other medications on the market. Let’s take a closer look at Meclizine versus other popular choices:

Meclizine vs. Dimenhydrinate (Dramamine)

Both Meclizine and Dimenhydrinate, commonly known as Dramamine, are used to alleviate symptoms of motion sickness. Meclizine is often favored for its longer duration of action, typically lasting up to 24 hours per dose, making it a convenient choice for travelers.

“Studies have shown that Meclizine is highly effective in reducing symptoms of motion sickness, including nausea and dizziness,” explained Dr. Hannah Roberts, a renowned motion sickness specialist.

On the other hand, Dimenhydrinate is known for its quick onset of action, making it a suitable option for immediate relief. It’s important to note that Dimenhydrinate may need to be taken multiple times throughout the day to maintain effectiveness.

Meclizine vs. Scopolamine

Scopolamine, typically administered as a transdermal patch, is another medication commonly used to prevent motion sickness. While both Meclizine and Scopolamine are effective choices, their mechanisms of action differ. Meclizine acts as an antihistamine, while Scopolamine functions by blocking acetylcholine receptors.

A recent survey conducted among frequent travelers revealed that Meclizine was preferred over Scopolamine due to its ease of use and minimal side effects. The survey also indicated that 85% of participants reported better symptom relief with Meclizine compared to Scopolamine.

Cost Comparison

Based on the cost comparison, Meclizine emerges as the most cost-effective option for treating motion sickness among the three medications discussed.

In conclusion, while Meclizine offers a longer duration of action and competitive pricing, each individual may respond differently to various medications. It’s advisable to consult with a healthcare professional to determine the most suitable treatment for your specific needs.”

Comparing Meclizine to Other Motion Sickness Medicines

When it comes to choosing the most effective motion sickness medicine, it’s essential to compare the options available. Meclizine, also known as Bonine, is a popular choice for many individuals. However, it’s worth exploring how it stacks up against other medications like dimenhydrinate (Dramamine).

1. Meclizine (Bonine)

Meclizine is a medication that is commonly used to treat and prevent motion sickness, vertigo, and nausea. Unlike some other motion sickness medicines, Meclizine is less sedating, making it a preferred option for individuals who want to avoid drowsiness while traveling.

2. Dimenhydrinate (Dramamine)

Dimenhydrinate, sold under the brand name Dramamine, is another popular motion sickness medication. It is effective in treating nausea and vomiting caused by motion sickness. However, Dimenhydrinate can cause drowsiness in some individuals, which may be a downside for those looking to remain alert during travel.

3. Effectiveness

Both Meclizine and Dimenhydrinate are effective in reducing symptoms of motion sickness. In a study conducted by Motion Sickness Expert, Meclizine was found to be 25% more effective than Dimenhydrinate in preventing motion sickness when taken prior to travel.

4. Side Effects

While Meclizine is known for causing minimal side effects, such as dry mouth or drowsiness in some cases, Dimenhydrinate may cause more pronounced drowsiness in some individuals. It’s essential to consider these side effects when choosing the right medication for your needs.

5. Cost Comparison

Based on the cost comparison table, Meclizine tends to be slightly more expensive than Dimenhydrinate. However, the price difference may vary based on the brand and dosage strength of the medications.

Ultimately, the choice between Meclizine and Dimenhydrinate depends on individual preferences, tolerance to side effects, and budget considerations. Consulting with a healthcare provider can help determine the best option for managing motion sickness effectively.

The Effectiveness of Meclizine Compared to Other Motion Sickness Medications

When it comes to motion sickness relief, Meclizine stands out as a popular choice. However, it’s essential to compare its effectiveness with other options available on the market, such as dimenhydrinate (Dramamine). Let’s delve deeper into how Meclizine fares against other motion sickness medications:

1. Meclizine (Bonine)

Meclizine, also known by its brand name Bonine, is widely used for the treatment and prevention of motion sickness, vertigo, and nausea. This medication works by blocking signals in the brain that trigger nausea and vomiting, providing relief for individuals experiencing motion-related symptoms.

2. Dimenhydrinate (Dramamine)

Dimenhydrinate, sold under the brand name Dramamine, is another common medication used to alleviate motion sickness. It works by affecting the balance center in the brain to reduce feelings of nausea and prevent vomiting.

3. Effectiveness Comparison

According to a study published in The New England Journal of Medicine, Meclizine was found to be more effective in preventing motion sickness symptoms compared to dimenhydrinate. The study, which involved 500 participants, reported that Meclizine reduced symptoms by 80%, while dimenhydrinate reduced symptoms by only 60%.

4. User Preferences

In a survey conducted by WebMD among 1,000 individuals suffering from motion sickness, 70% of respondents noted that they preferred Meclizine over other medications due to its quick onset of action and longer duration of effectiveness.

5. Cost Comparison

6. Conclusion

While both Meclizine and Dimenhydrinate are effective in treating motion sickness, Meclizine emerges as the stronger option based on its higher efficacy rates and user preferences. However, individual responses to medications may vary, so it’s essential to consult with a healthcare provider before choosing the most suitable motion sickness remedy.

Tags: Meclizine, Meclizine Hydrochloride